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doi: 10.3389/fendo.2022.904312 134 XieYLiangBMengZGuoRLiuCYuanYet al

Blocking excessive activation of this factor is a key target for effectively inhibiting the activation of the contact system, and the use of novel inhibitory antibodies to neutralize FXIIa has been shown to reduce the inflammatory response in animal models of ECMO, as well as thrombosis prevention (52, 53)

El inconveniente sera el enmascaramiento del diagnstico neonatal, es decir, no apareceran los signos bioqumicos que permitan confirmar el diagnstico inmediatamente despus del nacimiento