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Availability: InStock
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SKU: 66388213836 · From www.marsberger-treibhaus.de

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The -cyano amide-based Michael acceptors have also been elegantly used by the Taunton group as warheads in small-molecule inhibitors to react with active site cysteines while being minimally affected by the high concentration of intracellular GSH due to the fast reaction kinetics and the mM of K d (refs 31, 32)

Biology 12(5):697 Li G, Guo J, Mou Y, Luo Q, Wang X, Xue W, Hou T, Zeng T, Yang Y (2024) Keratin gene signature expression drives epithelial-mesenchymal transition through enhanced TGF- signaling pathway activation and correlates with adverse prognosis in lung adenocarcinoma