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This localized hypoxia (lack of oxygen) forces cells to switch to anaerobic energy production, generating excessive lactic acid and causing rapid, severe muscle fatigue even after minimal physical exertion

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Disclosures: Nicholas Smith: Nothing to Disclose, Andrew Schreiner: Nothing to Disclose, David Koch: Nothing to Disclose 2054 DIFFERENTIATING EARLY-STAGE CIRRHOSIS FROM NON-CIRRHOTIC PORTAL HYPERTENSION USING NON-INVASIVE DIAGNOSTIC TESTS Dilara Turan Gokce 1 Derya Ari 1 Ilkay Idilman 2 Meral Akdogan 3 , 1 Ankara Bilkent City Hospital, 2 Hacettepe University, School of Medicine, 3 Ankara Bilkent City Hospital, University of Health Science Background: This study aims to evaluate the effectiveness of non-invasive diagnostic tests, including Fibroscan, FIB-4, APRI, and MR elastography, in distinguishing between patients with non-cirhotic portal hypertension and cirhotic patients with Child-Pugh A