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At the same time, limitations remain obvious: clinical data are still insufficient, most conclusions are based on experimental models, and questions of long-term safety, application protocols, and effectiveness at later stages of degeneration require additional research

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Severe or persistent symptoms may require medical attention and should be reported to your healthcare provider. Patients with certain health conditions or on specific medications should always talk with their healthcare provider before starting B12 injections to avoid interactions and ensure the treatment is appropriate