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These include phenytoin, which warrants separate consideration (Table 11).57 Another neuromodulator that is increasingly used in daily practice is lacosamide, both orally and intravenously.58 Local infiltration Local infiltration of botulinum toxin A in the painful area may be an interesting therapeutic option, given the pathophysiology of TN and the drugs results in models of neuropathic pain, with the potential to reduce the transmission of ephaptic impulses and to desensitise trigger points