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the subsequent overload of ROS induces mitochondrial dysfunction and triggers the apoptotic cascade

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They found that the levels of peroxidase and superoxide dismutase enzymes increased, but catalase enzyme activity decreased

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Marcotti et al., 2023

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In mitochondria, Ca 2+ uptake is performed by mUP, also controlled by cytosolic Ca 2+ and by Ca 2+ /calmodulin

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