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Fisher M, VandenBranden M, Findlay K, Burchell B, Thummel K, Hall S, Wrighton SA: Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank

The tissue sections from all experimental groups were dewaxed and hydrated (Alomar et al., 2021)

Despite their clinical significance, their use in anticancer therapies is limited due to negative consequences, such as dose-limiting toxicities and drug resistance in the case of type I inhibitors [75]and the development of secondary malignancies when treated with type II inhibitors [76] (Fig