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Although the underlying mechanisms of this metabolic shift remain to be fully elucidated, these findings collectively suggest that the regulation of glycolysis affects PASMC proliferation and migration, thereby contributing to vascular remodeling

doi: 10.1046/j.1365-2265.2002.01654.x 195 SamuelsMHSchuffKGCarlsonNECarelloPJanowskyJS

During this process, electrons are transferred sequentially across a series of protein complexes, a mechanism that can inadvertently result in ROS formation