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Neurite outgrowth in PC12 cells stimulated by acetyl-L-carnitine arginine amide Neurochem Res 1995

J Neurotrauma 1992

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Specifically, SIRT3 deacetylates and inhibits aldehyde dehydrogenase 2, which prevents the conversion of acetaldehyde to acetate, potentially leading to acetaldehyde toxicity 183