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GuanJHuangXDongJLuHLinYLiuMet alA novel mouse model of hyperuricemia and gouty nephropathy

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The in-vivo part of the study lasted 11 days

160 Additionally, human nuclear factor with BRCT domain protein 1 (NFBD1), an amplifier of the p53 pathway and also known as a mediator of DNA damage checkpoint protein (MDC1), is vital for protecting cells from apoptosis in NPC cells mediated through the p53-ROS-mitochondrial pathway