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Prog Mol Subcell Biol 12: 113-134

Extract of Hedyotis diffusa Willd influences murine leukemia WEHI-3 cells in vivo as well as promoting T- and B-cell proliferation in leukemic mice

Glutathione has been administered intravenously to treat chronic liver disease in humans

Mounting data reveal intimate Nrf2NLRP3 crosstalk: Nrf2 activation limits the transcriptional priming of NLRP3, curtails mitochondrial ROS, and directly interferes with inflammasome assembly, whereas unchecked NLRP3 signaling feeds forward to inhibit Nrf2 and perpetuate oxidative damage (sciencedirect.com)