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Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes. Science translational medicine 9, no

Member (20032015) Indiana University School of Medicine Vice-Chair of Clinical Practice, Department of Neurology Development (20032005) Indiana University School of Medicine Department of Neurology Clinical Practice Committee (incentive plan, coding, compensation, service standards)

Consistent with the results observed in in vivo experiments, GHK-Cu significantly restored Nrf2 expression in the cytoplasm and reduced it in the nucleus while significantly reducing Keap1 levels in the cytoplasm compared with the CSE-exposed cells without GHK-Cu (Figures 6DF)

consistent with Gpx4s role as the master regulator of ferroptosis, motor neuron degeneration induced by Gpx4 ablation exhibited characteristics of ferroptosis 14