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Availability of supporting data The data sets supporting the results of this article are available in the ArrayExpress repository (European Bioinformatics Institute, Cambridge, UK) [56] with series accession number E-MTAB-1864 ( Abbreviations ACTH: Adrenocorticotropic hormone

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Patients should be closely monitored for signs of adverse effects during therapy

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Abstract Providing NO-system importance, we suggest that one single application of the NOS-blocker L-NAME may induce retinal ischemia in rats, and that the stable pentadecapeptide BPC 157 may be the therapy, since it may interact with the NO-system and may counteract various adverse effects of L-NAME application

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