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Description

Interestingly a mutation, Phe827Leu, found in a PAIS patient, displayed an unexpected increased N/C interaction and TIF2 coactivation (290)

Mooijaart, S

Me-DTC may act as an irreversible inhibitor of aldehyde dehydrogenases (ALDH1), whereas the sulfoxide and sulfone metabolites, especially the sulfone metabolite, may be more potent inhibitors of both ALDH 1, and ALDH2

Fixation was carried out by incubating the cells with 4% paraformaldehyde in PBS containing 0.1% saponin for 45 min at 4 C, followed by washing with PBS supplemented with 0.1% saponin and 1% BSA (SBP)