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Furthermore, gasdermins, which regulate inflammatory form of cell death, were upregulated in the brains of GCLC-KO mice, suggesting the contribution of pyroptosis to neuronal cell death in these animals

10.1038/s41591-024-03169-2 19 ChenY.-R.ZweierJ

There are two types of biochemical mechanism of insecticide resistance outlined [96,97].The first is by selection of an altered target molecule so that no interaction between the molecules and the toxins occurs, resulting in target site resistance