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Abbreviations The following abbreviations are used in this manuscript: Author Contributions Conceptualization, G.S

contributing etiological viscerosomatic disturbances within clinical presentations

(Qiu et al., 2023) reported low levels of NAD + in the aorta from hypertensive patients showing that supplementation with NAD + precursors effectively lowered blood pressure and improved impaired vascular function in both hypertensive patients and mice

IGF-1 LR3 may also be able to regulate the metabolism of various compounds and thus ensure that tissues receive a greater amount of nutrients, using them better