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More importantly, oxidant enzymes including mitochondrial electron transport chain complex I, complex II, complex III, as well as SODs, xanthine oxidase (XO), NO synthases (NOS), cytochrome p 450 enzymes (CYP), NADPH oxidases (NOX) and lipoxygenase (LOX), generate O 2 radicals which are quickly converted into H 2 O 2 , OH and other radicals [26]

These lines of evidence and decision-making tools can be used to identify priorities and next steps to advance a given technology, assess whether a technology is ready for field demonstration, and identify key areas of uncertainty regarding technology performance

ROO primarily targets the polyunsaturated fatty acids (PUFA) found in DNA bases and cell membranes, but it also targets almost all important groups of biomolecules

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