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However, the downregulated proteins exhibited enrichment in metabolic pathways, particularly the catabolic process ( p adjusted = 0.0011), cellular catabolic process ( p adjusted = 0.0006), and cytoplasmic translation ( p adjusted = 3.2E-07) (Supplementary Figure S6C

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Glutathione (reduced L-glutathione, the biologically active form) predates DSHEA and is therefore grandfathered as a permissible supplement ingredient