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Public Health 13 , 727 (2016)

Systemic Therapy (Severe / Refractory) Methotrexate (weekly oral/injection), cyclosporine for rapid clearance, acitretin for pustular/erythrodermic types

For example, fluoxetine, a SSRI commonly used for psychiatric disorder, is considered to have neuroprotective effects, thereby decreasing fatigue symptoms in patients with MS (87)

Several FINs have been licensed by the FDA to be utilized in clinics, and they have shown remarkable efficacy as a revolutionary anticancer treatment for a range of carcinomas