glutathione napqui Silymarin prevents acetaminophen-induced hepatotoxicity via up-regulation of the conjugation capacity in mice Paracetamol metabolites. NAPQI: N-acetyl-p-benzo-quinone-imine; UGT:...

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Quite remarkably, in those with low POP levels, the typically robust association between diabetes and obesity was not observed in a nested case-controlled study, suggesting that obesity may exaggerate the metabolic disturbances caused by POPs (perhaps because adipose tissue provides a reservoir for fat-soluble toxins), rather than being directly responsible for the altered metabolism

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Chronic neuroinflammation can sustain oxidative stress and neuronal damage, creating a feedback loop that exacerbates disease progression [164]