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metabolic & oncology research [7][8][9]

Acute Vhl gene inactivation induces cardiac HIF-dependent erythropoietin gene expression

It has been found that low vitamin B12 levels can cause a variety of dermatologic disturbances, including hyperpigmentation, nail discoloration, and the loss of skin color in the form of patches i.e

Activation of these membrane receptors triggers downstream changes in mitogen-activated protein kinase (MAPK) and phosphatidyl-inositol-3-kinase/AKT (PI3K/AKT) pathways, ultimately influencing gene transcription 61,62