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In CNS-relevant models, melanocortin receptor activation is used to probe appetite suppression and neuroendocrine arousal circuitry, including receptor desensitization dynamics in time-course assays

The copper- and zinc-containing cytosolic SOD (Cu/Zn SOD, SOD1) is a 32 kDa homodimer abundantly expressed in astrocytes and present in plasma, lymph, and cerebrospinal fluids [14]