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Under normal conditions, mCherry-EGFP-RAMP4 localized to the ER, with both mCherry and EGFP fluorescence detectable in most cells (Fig

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Figure 2 4 Pathogenesis and tumor microenvironment Breast cancer is an ecosystem that contains both malignant cells and stromal cells and are characterized by a substantial change in the surrounding stroma, or TME, essential for cancer growth and progression