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Additionally, further work is needed to fully elucidate the molecular mechanisms underlying this compound's diverse biological effects and to establish its potential relevance to human health and disease

Early NRTIs such as Zidovudine (AZT), Stavudine (d4T) and Didanosine (ddI) had a higher affinity for Pol- and consequently produced substantial mitochondrial toxicities, including lactic acidosis, hepatic steatosis, peripheral neuropathy, and lipoatrophy (104, 105)

[DOI] [PubMed] [PMC] Dahlgren KN, Manelli AM, Stine WB Jr, Baker LK, Krafft GA, LaDu MJ

They include: Single-leg stands to improve balance and stability Heel-to-toe walks to enhance coordination and balance Balance boards or BOSU ball training to challenge balance and stability These exercises can be tailored to fit different needs and abilities