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Supraspinal neuropathological findings have been reported in patients with severe SMA, overall suggesting that the lack of SMN has widespread consequences and manifestations in the central nervous system (CNS) that are not limited to lower motor neurons (LMNs) [10,11,12]

Institute BCN presents L-carnitine as an essential active ingredient for metabolising fat and mobilising fatty acids into the cell, where fat is converted into energy

Some patients remain asymptomatic for long time even without therapy, but are at risk of sudden death due to cardiac arrhythmia.

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