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Gli studi su colture di cellule della pelle mostrano che il peptide stimola la sintesi e la degradazione controllata di collagene , glicosaminoglicani e altri componenti della matrice extracellulare come proteoglicani e condroitin solfato

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Indeed, numerous investigations reveal that force production during submaximal tetanic contractions is depressed by NO donors (8, 20, 222, 300, 338) whereas muscle force production is increased by NOS inhibitors and NO scavengers (20, 221)