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A higher pre-drug urinary level of the compound taurine was associated with a lower degree of hepatotoxicity, whereas a higher pre-drug level of trimethylamine-N-oxide and betaine was associated with a greater severity of liver damage

Pommerville, BA, MD, FRCS(C), Consultant Urologist, Vancouver Island Health Authority, Victoria, BC

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Importantly, the announcement does not indicate that the peptides will be placed on the Category 1 May Compound list, possibly leaving those bulk drug substances in limbo unless the FDA announces enforcement discretion with regard to the substances