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In the first clinical study on BBB disruption using LITT, the permeability of the BBB increased after hyperthermia, with higher permeability peaking a few days to a few weeks after the procedure 119

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He was educated at Bangalore University (bachelor's degree in electrical engineering 1967), the Indian Institute of Science Bangalore (masters degree 1970), and Yale University (MPhil 1973 and PhD 1977)