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Benefits may persist for some time after discontinuation, particularly the cognitive improvements potentially rooted in BDNF-mediated neuroplastic changes

~5-fold potency at

Neuroprotective effects of lixisenatide and liraglutide in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinsons disease

Third, individual variation is substantial: patients with severe insulin resistance or significant mitochondrial dysfunction may respond at lower doses than metabolically healthy athletes