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doi: 10.3389/fneur.2018.01081 151 ShaheenH

Am J Heal Pharm

The areas most often affected are: the fingers and wrists in the armpits groin and genitals around the mouth and eyes inside the mouth

Th2 cells are particularly crucial in this context, because they produce interleukins such as IL-4 and IL-13, which are known to promote fibroblast activation and collagen synthesis, fundamental events in fibrosis development (107)