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Description

Gentiopicroside produces endothelium-independent vasodilation by deactivating the pi3k/akt/rho-kinase pathway in isolated rat thoracic aorta

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Therefore, future research targeting glutamine metabolism should focus on how to inhibit multiple metabolic pathways without affecting normal cells to achieve effective treatment for AML

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In addition, the use of AKT inhibitors in combination with extracellular asparagine (ASN) depletion can significantly inhibit tumor growth (Fig

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10.3389/fphar.2020.570555 192 ZhuW.BuffaJ

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