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Notably, GLS-mediated deamination of glutamine to glutamate is the first and rate-limiting step of glutaminolysis, making it an attractive druggable target 9

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Chronic altitude illness CMS Unlike acute altitude illnesses, research on the genetic basis of CMS is limited, with only a few studies exploring the link between CMS susceptibility and several genes, including SENP1 , ACE , AGT , and VEGFA (Table 1)

Rev-Erb : NR1D (nuclear receptor subfamily 1 group D)