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Engineering a humanized bispecific F(ab)2 fragment for improved binding to T cells

The approved antifibrotic agent nintedanib may also influence this pathway by improving the ADMA/arginine ratio, enhancing NOS activity, restoring NO levels, and reducing oxidative stress [142]

Together, these data suggest that host glutathione is critical for rickettsial septation, actin-based motility, avoiding ubiquitylation, and survival in immune cells