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Additionally, lower responses to anti-CD38 antibodies have been associated with low CD38 expression

Some common signs of B12 deficiency include: Chronic fatigue and low energy Brain fog and difficulty focusing Mood swings, anxiety, or irritability Tingling or numbness in hands and feet Poor sleep or insomnia Weakened immune system (getting sick often) Many people, especially vegans, vegetarians, older adults, and those with digestive issues , are more at risk of B12 deficiency