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REDEFINE 2 evaluated the combination in adults with overweight or obesity who also had type 2 diabetes over a comparable 68-week design [6]

Striae rubrae early, red/pink marks with active blood vessels most responsive to treatment Striae albae older, white/silvery marks harder to treat (collagen already broken down) Striae gravidarum pregnancy-related, commonly on belly, breasts and thighs Striae nigrae / caerulea dark-brown/black or bluish marks, more common on darker skin tones (may need pigment-aware care ) Striae atrophicans thin-skin marks linked to conditions like Cushings or steroid overuse Identifying the type helps tailor treatment early red marks have the best response rates, which is why acting sooner helps

Localization NPs were performed using a confocal laser scanning microscopy (LSM-880, ZEISS)

D Size For Womens Shoes In women's footwear, D means the shoe is wide