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In addition, the involvement of active oxygen species as secondary messengers for toxicity was investigated [346] and the prevention of such toxicity by scavengers of active oxygen species was also presented [347]

10.3109/15622975.2010.518626 144 MishraS

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For example, it has been shown that exceeding the upper limit of selenium intake (400 g/d) can lead to selenotoxicity, but no significant symptoms of toxicity were observed when selenium was ingested in the form of SeNPs (1,600 g/d), and some selenotoxicity symptoms did not occur until even an intake of 3,200 g/d (255)