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In this review, we will present available evidence on the similarities and differences existing between isatuximab and daratumumab, ranging from their mechanisms of action to translational results, and an overview of recent, key clinical study findings for each agent, to better define their role in the management of patients with RRMM

FDA has published a technical specifications document entitled "Submitting Clinical Trial Datasets to Evaluate the Impact of Immunogenicity on the Pharmacokinetics of a Drug," intended to help support the regulatory evaluation of immunogenicity data

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Beyond clinical data, acupunctures rationale is grounded in TCM theory, which conceptualises HT as a disorder of spleen and kidney yang deficiency or liver qi stagnation leading to phlegm obstruction. These imbalances are thought to disrupt the bodys internal harmony and immune defence