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It also extends to non-psychiatric FIASMs, showing that the benefit is not tied to mood disorder treatments but may relate to shared FIASMA-associated properties, while remaining compatible with additional off-target mechanisms

The potential of L-Carnitine in managing IR appears to increase with prolonged use, although further long-term studies are needed to confirm these findings

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It is known to activate major cascades like PI3 kinase-AKT, RAS-RAF-MEK-ERK, and STATs cascades 35 , and has been hypothesized that it also activates the NFB signaling cascade 36 , which is a well-known inflammatory and oxidative stress pathway