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Interestingly, ALS and frontotemporal dementia (FTD) are closely related conditions and often share both genetic and disease mechanisms, especially in people with C9ORF72 mutations suggesting they may be part of the same disease spectrum (Parobkova and Matej, 2021)

Molecular and therapeutic aspects of hyperbaric oxygen therapy in neurological conditions

Yamada (Haebarucho, Japan) Objective: To present a young adolescent female with functional dystonia phenotype progressed to status dystonicus(SD)/anarthria and mental confusion, even more molecular genetics appeared the de novo pathogenic variant of GNAOI gene

15 HIF-1 consists of HIF-1 and HIF-1 subunits, which interact with the hypoxia-responsive element (HRE) to further modulate the expression of target genes