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Beyond iron handling, NRF2 modulates the GSH antioxidant system by inducing the expression of enzymes required for GSH biosynthesis, such as glutamatecysteine ligase catalytic and modifier subunits (GCLC/GCLM), glutathione synthase (GSS), and the cystine/glutamate antiporter subunit SLC7A11 [114]

In addition, the Stroop test has good testretest reliability, and it has the advantage that it can be easily administered using a smartphone

7OH can be readily rearranged to mitragynine pseudoindoxyl with zinc triflate as reported by us previously 16 , however this pseudoindoxyl system afforded C12 borylation (Fig