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153 Patchoulene epoxide significantly reduces the disease activity index and alleviates colon atrophy in ulcerative colitis mice, improving pathological changes in the colon and liver by protecting tight junctions and mucus connections and inhibiting pro-inflammatory cytokine and LPS generation

This exploration is pivotal for laying the groundwork for developing potential regulatory small molecules aimed at modulating palmitoylation levels through gene expression regulation, with the dual aim of controlling tumour progression and enhancing the efficacy of therapeutic interventions

Although the structure of the active site in synthetases can bind d-amino acids, it usually imposes a physical constraint that does not promote tRNA charging

Wilcox, G