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Effects of recombinant human interleukin 7 on T-cell recovery and thymic output in HIV-infected patients receiving antiretroviral therapy: results of a phase I/IIa randomized, placebo-controlled, multicenter study

Hierarchical clustering of all DEGs further corroborated this observation, revealing clear demarcation between infected and uninfected samples alongside a polarized red-blue expression patterncharacteristic of directional reprogramming toward either pro-viral or anti-viral states ( Figure 3B )

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Methods: Adults aged 18-75 yr with BMI 30 or 27 kg/m 2 and 1 weight-related condition (T2D excluded) were randomly assigned to 48 wk of QW sc RETA (1, 4, 8 or 12 mg) or PBO