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Our role is to help patients navigate this, because management is not one-size-fits-all: Less Severe (e.g., mild dermatitis , pruritus): Often managed with topical therapies and close monitoring while continuing treatment

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For context, the fat-mass reductions reported in Billon 2024 roughly 25-30% in diet-induced obese mice over 28 days without exercise are large for a preclinical metabolic agent and explain why the "exercise mimetic" label stuck