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241 A UNA supports RNase H activity, which is beneficial for antisense-based nucleic acid therapies

Emphasis will be placed on the metabolic pathways and relevant players (Table 1) that interfere with cysteine anabolism and catabolism, and the determinants that affect cysteine bioavailability, thereby influencing cancer development

The C-terminal segment takes part in interactions with the N-terminal -helix of the extracellular domain, the extracellular tip of the transmembrane helix 1 of the GLP-1 receptor, and the extracellular loop 1 of the GIP receptor