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185198 Anderson, The Risk of Alcohol Science NetLinks, Alcohol and the Human Body, Circulatory System NHS Digital, Statistics on Alcohol, England 2020 (2020) Science NetLinks, Digestive system Kurose I, Higuchi H, Kato S, Miura S, and Ishii H, Ethanol-induced oxidative stress in the liver, Alcoholism: Clinical and Experimental Research (1996), Volume 20: Issue 1, 77A85A Ringborg U, Alcohol and the risk of cancer, in Alcoholism: Clinical and Experimental Research (1998), Volume 22, 323S328S Science NetLinks, Digestive system Jensen TK, et al., Does moderate alcohol consumption affect fertility?, British Medical Journal (August 1998), Volume 317, pp

As noted below, the health risks of cigarette smoking are massive

Several studies have shown that endothelial function assessed by biomarkers for endothelial function including circulating levels of nitrate/nitrite, NO, von Willebrand factor (vWF), cellular adhesion molecules, vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1), endothelial progenitor cells (EPCs) and endothelial microparticles (EMPs), endothelin-1 and activity of endothelial NOS (eNOS) other than physiological assessment for endothelial function was impaired in smokers