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The skin at early developmental stages consists of two epithelial layers, each with distinct functions and morphologies

Se ha demostrado en estudios en animales que las aminas cuaternarias no absorbidas, como la colina, la fosfatidilcolina, la betana o la l-carnitina, pueden ser metabolizadas por microorganismos intestinales para producir el compuesto intermedio trimetilamina (TMA)

Notably, PKM1 is the most abundantly expressed isoform in neuronal cells under normal physiological conditions, whereas PKM2 is relatively less expressed