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Description

For a knee tendon issue, injection in the tissue surrounding the knee may provide localized benefit

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Funding This study was supported by the National Natural Science Foundation of China (82104534, 81903902) and the Sichuan Province Science Research Special Funding Project for Postdoctoral Fellows (2022BSH044)

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Hexosamine biosynthetic pathway The hexosamine biosynthetic pathway (HBP) is an alternative secondary route within glucose metabolism that processes fructose-6-phosphate (F6P) and glutamine into glucosamine-6-phosphate (G6P) through the enzymatic action of glutaminefructose-6-phosphate transaminase (GFPT), present in the forms of GFPT1 and GFPT2, with GFPT2 being the primary isoform active in cardiac tissue [90]

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Both methods have been used to transform [13C6]aniline into folic acid, labelled with [13C6] in the p-aminobenzoate moiety, and [3,3,4,4-2H4]-L-glutamic acid into folic acid, labelled with [2H4] in the glutamate moiety

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