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Moreover, AGK2 treatment attenuated the NAD + -induced increases in the Nrf2 mRNA levels and the nuclear Nrf2 levels (Figures 4JL)

Acknowledgments We wish to thank Prof

Those types of desensitization are related to different mechanisms especially in terms of receptor phosphorylation and kinases (Chu et al., 1997)

Therefore, they work harmoniously to combat age-related decline, promote cellular energy production, enhance metabolic health, and support cognitive function