lower zinc levels when glutathione is taken long-term causes acute impairment of metabolism followed by coordinated antioxidant defenses amplification in gills of brown mussels Perna perna Zinc deficiency as possible link

Quercetin metabolites have been found to inhibit the transcription of genes such as S14, FAS, apolipoprotein CIII, and transferrin (45, 47)

Furthermore, epigenetic mechanismsincluding DNA methylation, histone acetylation, histone protein variants, and siRNAexert dual regulatory effects: (1) indirectly influencing flavonoid synthesis by altering the expression of pathway-related genes through the MBW complex, and (2) directly regulating structural genes (e.g., CHS, FLS) that encode rate-limiting enzymes in the flavonoid biosynthetic pathway

The effect of N-acetylcysteine (NAC) on human cognition - A systematic review

doi: 10.3390/nu11112837