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NAC, with its strong antioxidant and immune-boosting properties, fits well within this trend

Bearpark MJ, Blancafort L, Robb MA

Recent studies have shown that at least one mechanism of colchicines action is by acting to prevent a cascade of reactions that lead to the production of interleukin 1-beta, which is an inflammatory protein (cytokine), which is important in gouty inflammation.8 When used as one or two tablets a day (0.6mg each), most people tolerate this medication well, and this dose can help prevent gout attacks

The evidence base is largely preclinical (animal and cell) research on the individual components, supplemented by practitioner-derived protocols